(most) holy (one, thing), saint

“Holy Ghost, Holy Spirit” From Concise Bible Dictionary:

The third Person in the Trinity, as seen in the formula of baptism (Matt. 28:1919Go ye therefore, and teach all nations, baptizing them in the name of the Father, and of the Son, and of the Holy Ghost: (Matthew 28:19)). The Spirit moved upon the face of the waters at the creation (Gen. 1:22And the earth was without form, and void; and darkness was upon the face of the deep. And the Spirit of God moved upon the face of the waters. (Genesis 1:2)); and He came upon certain persons in the Old Testament to fulfill the purposes of God. David asked that the Holy Spirit might not be taken from him (Psa. 51:1111Cast me not away from thy presence; and take not thy holy spirit from me. (Psalm 51:11)); which stands in contrast to the indwelling of the Holy Spirit in Christians, for He abides with them. It is by the operation of the Spirit that they are born anew, and He is the seal of their faith in Christ, and the earnest of their inheritance above (John 3:55Jesus answered, Verily, verily, I say unto thee, Except a man be born of water and of the Spirit, he cannot enter into the kingdom of God. (John 3:5); Eph. 1:13-1413In whom ye also trusted, after that ye heard the word of truth, the gospel of your salvation: in whom also after that ye believed, ye were sealed with that holy Spirit of promise, 14Which is the earnest of our inheritance until the redemption of the purchased possession, unto the praise of his glory. (Ephesians 1:13‑14)). He is their COMFORTER or Advocate (παράκήτος, one who manages their affairs) on earth, as Christ is the same in heaven (John 14:16, 2616And I will pray the Father, and he shall give you another Comforter, that he may abide with you for ever; (John 14:16)
26But the Comforter, which is the Holy Ghost, whom the Father will send in my name, he shall teach you all things, and bring all things to your remembrance, whatsoever I have said unto you. (John 14:26)
Though the Holy Spirit influenced and came upon the Old Testament saints, He did not come personally until Christ had ascended (John 16:77Nevertheless I tell you the truth; It is expedient for you that I go away: for if I go not away, the Comforter will not come unto you; but if I depart, I will send him unto you. (John 16:7)). Many passages prove His personality—a matter of great importance, often lost sight of by those who constantly speak of Him as an influence. Ananias lied to the Holy Spirit (Acts 5:33But Peter said, Ananias, why hath Satan filled thine heart to lie to the Holy Ghost, and to keep back part of the price of the land? (Acts 5:3)). “The Holy Ghost said, Separate me Barnabas and Saul” (Acts 13:22As they ministered to the Lord, and fasted, the Holy Ghost said, Separate me Barnabas and Saul for the work whereunto I have called them. (Acts 13:2)). “Dividing.... as He will” (1 Cor. 12:1111But all these worketh that one and the selfsame Spirit, dividing to every man severally as he will. (1 Corinthians 12:11)). The Holy Spirit directed the labors of Paul and his companions (Acts 16:6-76Now when they had gone throughout Phrygia and the region of Galatia, and were forbidden of the Holy Ghost to preach the word in Asia, 7After they were come to Mysia, they assayed to go into Bithynia: but the Spirit suffered them not. (Acts 16:6‑7)), and the Lord Jesus cast out demons by the Spirit of God (Matt. 12:2828But if I cast out devils by the Spirit of God, then the kingdom of God is come unto you. (Matthew 12:28)).
His presence and operations here are some of the fruits of Christ’s exaltation. He forms Christ in the believer. He is also the power of life and the power for testimony. Indwelling the saints individually, He forms them collectively into one body, they are also builded together for a habitation of God through the Spirit (1 Cor. 3:1616Know ye not that ye are the temple of God, and that the Spirit of God dwelleth in you? (1 Corinthians 3:16); Eph. 2:2222In whom ye also are builded together for an habitation of God through the Spirit. (Ephesians 2:22)).
To be indwelt by the Holy Spirit is an immense favor, for He is a divine Person: any one so indwelt is not in the flesh, but in the Spirit. He is the Spirit of sonship and by Him the believer cries, Abba Father. Christians are exhorted to be guided by Him, and neither to quench nor to grieve that holy One. Our responsibility is to “walk in the Spirit” (Gal. 5:1616This I say then, Walk in the Spirit, and ye shall not fulfil the lust of the flesh. (Galatians 5:16)).

“Saint” From Concise Bible Dictionary:

Two words are employed in the Hebrew.
2. qadosh, “consecrated, set apart, holy” (Deut. 33:33Yea, he loved the people; all his saints are in thy hand: and they sat down at thy feet; every one shall receive of thy words. (Deuteronomy 33:3); Job 15:1515Behold, he putteth no trust in his saints; yea, the heavens are not clean in his sight. (Job 15:15); Psa. 16:33But to the saints that are in the earth, and to the excellent, in whom is all my delight. (Psalm 16:3); Psa. 34:99O fear the Lord, ye his saints: for there is no want to them that fear him. (Psalm 34:9); Psa. 89:5,75And the heavens shall praise thy wonders, O Lord: thy faithfulness also in the congregation of the saints. (Psalm 89:5)
7God is greatly to be feared in the assembly of the saints, and to be had in reverence of all them that are about him. (Psalm 89:7)
; Dan. 7:18-2718But the saints of the most High shall take the kingdom, and possess the kingdom for ever, even for ever and ever. 19Then I would know the truth of the fourth beast, which was diverse from all the others, exceeding dreadful, whose teeth were of iron, and his nails of brass; which devoured, brake in pieces, and stamped the residue with his feet; 20And of the ten horns that were in his head, and of the other which came up, and before whom three fell; even of that horn that had eyes, and a mouth that spake very great things, whose look was more stout than his fellows. 21I beheld, and the same horn made war with the saints, and prevailed against them; 22Until the Ancient of days came, and judgment was given to the saints of the most High; and the time came that the saints possessed the kingdom. 23Thus he said, The fourth beast shall be the fourth kingdom upon earth, which shall be diverse from all kingdoms, and shall devour the whole earth, and shall tread it down, and break it in pieces. 24And the ten horns out of this kingdom are ten kings that shall arise: and another shall rise after them; and he shall be diverse from the first, and he shall subdue three kings. 25And he shall speak great words against the most High, and shall wear out the saints of the most High, and think to change times and laws: and they shall be given into his hand until a time and times and the dividing of time. 26But the judgment shall sit, and they shall take away his dominion, to consume and to destroy it unto the end. 27And the kingdom and dominion, and the greatness of the kingdom under the whole heaven, shall be given to the people of the saints of the most High, whose kingdom is an everlasting kingdom, and all dominions shall serve and obey him. (Daniel 7:18‑27); Dan. 8:1313Then I heard one saint speaking, and another saint said unto that certain saint which spake, How long shall be the vision concerning the daily sacrifice, and the transgression of desolation, to give both the sanctuary and the host to be trodden under foot? (Daniel 8:13); Hos. 11:1212Ephraim compasseth me about with lies, and the house of Israel with deceit: but Judah yet ruleth with God, and is faithful with the saints. (Hosea 11:12); Zech. 14:55And ye shall flee to the valley of the mountains; for the valley of the mountains shall reach unto Azal: yea, ye shall flee, like as ye fled from before the earthquake in the days of Uzziah king of Judah: and the Lord my God shall come, and all the saints with thee. (Zechariah 14:5)). Aaron is called “the saint of Jehovah” (Psa. 106:1616They envied Moses also in the camp, and Aaron the saint of the Lord. (Psalm 106:16)).
In the New Testament the word used is ἅγιος, which means “holy one.” A saint is one set apart for God; he is such by calling—not “called to be a saint” (Rom. 1:77To all that be in Rome, beloved of God, called to be saints: Grace to you and peace from God our Father, and the Lord Jesus Christ. (Romans 1:7); 1 Cor. 1:22Unto the church of God which is at Corinth, to them that are sanctified in Christ Jesus, called to be saints, with all that in every place call upon the name of Jesus Christ our Lord, both theirs and ours: (1 Corinthians 1:2); compare Heb. 3:11Wherefore, holy brethren, partakers of the heavenly calling, consider the Apostle and High Priest of our profession, Christ Jesus; (Hebrews 3:1)). Saints are thus a distinct, recognized class of persons belonging to God—His saints (Acts 9:1313Then Ananias answered, Lord, I have heard by many of this man, how much evil he hath done to thy saints at Jerusalem: (Acts 9:13); Col. 1:2626Even the mystery which hath been hid from ages and from generations, but now is made manifest to his saints: (Colossians 1:26); 1 Thess. 3:1313To the end he may stablish your hearts unblameable in holiness before God, even our Father, at the coming of our Lord Jesus Christ with all his saints. (1 Thessalonians 3:13); Jude 1:1414And Enoch also, the seventh from Adam, prophesied of these, saying, Behold, the Lord cometh with ten thousands of his saints, (Jude 14)). All Christians are embraced in this class, so that the apostle could speak of “all saints” (Eph. 1:1515Wherefore I also, after I heard of your faith in the Lord Jesus, and love unto all the saints, (Ephesians 1:15); Eph. 3:1818May be able to comprehend with all saints what is the breadth, and length, and depth, and height; (Ephesians 3:18); Col. 1:44Since we heard of your faith in Christ Jesus, and of the love which ye have to all the saints, (Colossians 1:4); Philem. 1:55Hearing of thy love and faith, which thou hast toward the Lord Jesus, and toward all saints; (Philemon 5)). Christians therefore need not shrink from acknowledging the designation by which God has been pleased to distinguish them, and should ever remember that there is a line of conduct that “becometh saints” (Rom. 16:22That ye receive her in the Lord, as becometh saints, and that ye assist her in whatsoever business she hath need of you: for she hath been a succorer of many, and of myself also. (Romans 16:2); Eph. 5:33But fornication, and all uncleanness, or covetousness, let it not be once named among you, as becometh saints; (Ephesians 5:3)). The word ἅγιος corresponds with the Hebrew qadosh. The word chasid corresponds more with ὅσιος, translated “holy” (1 Tim. 2:88I will therefore that men pray every where, lifting up holy hands, without wrath and doubting. (1 Timothy 2:8); Titus 1:88But a lover of hospitality, a lover of good men, sober, just, holy, temperate; (Titus 1:8); Heb. 7:2626For such an high priest became us, who is holy, harmless, undefiled, separate from sinners, and made higher than the heavens; (Hebrews 7:26); Rev. 15:44Who shall not fear thee, O Lord, and glorify thy name? for thou only art holy: for all nations shall come and worship before thee; for thy judgments are made manifest. (Revelation 15:4)); and “Holy One” (Acts 2:2727Because thou wilt not leave my soul in hell, neither wilt thou suffer thine Holy One to see corruption. (Acts 2:27); Acts 13:3535Wherefore he saith also in another psalm, Thou shalt not suffer thine Holy One to see corruption. (Acts 13:35)).

Strong’s Dictionary of Greek Words:

from ἅγος (an awful thing) (compare 53, 2282); sacred (physically, pure, morally blameless or religious, ceremonially, consecrated)
KJV Usage:
(most) holy (one, thing), saint