(most) holy (one, thing), saint

Boyd’s Bible Dictionary:

(sanctified). In O. T., a pious Jew (Psa. 16:3). In N. T., a Christian believer (Rom. 1:7; 8:27; Heb. 6:10).

“Holy Ghost, Holy Spirit” From Concise Bible Dictionary:

The third Person in the Trinity, as seen in the formula of baptism (Matt. 28:19). The Spirit moved upon the face of the waters at the creation (Gen. 1:2); and He came upon certain persons in the Old Testament to fulfill the purposes of God. David asked that the Holy Spirit might not be taken from him (Psa. 51:11); which stands in contrast to the indwelling of the Holy Spirit in Christians, for He abides with them. It is by the operation of the Spirit that they are born anew, and He is the seal of their faith in Christ, and the earnest of their inheritance above (John 3:5; Eph. 1:13-14). He is their COMFORTER or Advocate (παράκήτος, one who manages their affairs) on earth, as Christ is the same in heaven (John 14:16, 26).
Though the Holy Spirit influenced and came upon the Old Testament saints, He did not come personally until Christ had ascended (John 16:7). Many passages prove His personality—a matter of great importance, often lost sight of by those who constantly speak of Him as an influence. Ananias lied to the Holy Spirit (Acts 5:3). “The Holy Ghost said, Separate me Barnabas and Saul” (Acts 13:2). “Dividing.... as He will” (1 Cor. 12:11). The Holy Spirit directed the labors of Paul and his companions (Acts 16:6-7), and the Lord Jesus cast out demons by the Spirit of God (Matt. 12:28).
His presence and operations here are some of the fruits of Christ’s exaltation. He forms Christ in the believer. He is also the power of life and the power for testimony. Indwelling the saints individually, He forms them collectively into one body, they are also builded together for a habitation of God through the Spirit (1 Cor. 3:16; Eph. 2:22).
To be indwelt by the Holy Spirit is an immense favor, for He is a divine Person: any one so indwelt is not in the flesh, but in the Spirit. He is the Spirit of sonship and by Him the believer cries, Abba Father. Christians are exhorted to be guided by Him, and neither to quench nor to grieve that holy One. Our responsibility is to “walk in the Spirit” (Gal. 5:16).
His presence on earth is a demonstration as to the world of sin, of righteousness, and of judgment (John 16:8-11).

“Saint” From Concise Bible Dictionary:

Two words are employed in the Hebrew.
1. chasid, “pious toward God,” also translated “holy” and “godly.” The word occurs frequently in the Psalms, where God speaks of His saints (Psa. 31:23; Psa. 50:5; Psa. 116:15; Psa. 149:1,5,9; etc.).
2. qadosh, “consecrated, set apart, holy” (Deut. 33:3; Job 15:15; Psa. 16:3; Psa. 34:9; Psa. 89:5,7; Dan. 7:18-27; Dan. 8:13; Hos. 11:12; Zech. 14:5). Aaron is called “the saint of Jehovah” (Psa. 106:16).
In the New Testament the word used is ἅγιος, which means “holy one.” A saint is one set apart for God; he is such by calling—not “called to be a saint” (Rom. 1:7; 1 Cor. 1:2; compare Heb. 3:1). Saints are thus a distinct, recognized class of persons belonging to God—His saints (Acts 9:13; Col. 1:26; 1 Thess. 3:13; Jude 1:14). All Christians are embraced in this class, so that the apostle could speak of “all saints” (Eph. 1:15; Eph. 3:18; Col. 1:4; Philem. 1:5). Christians therefore need not shrink from acknowledging the designation by which God has been pleased to distinguish them, and should ever remember that there is a line of conduct that “becometh saints” (Rom. 16:2; Eph. 5:3). The word ἅγιος corresponds with the Hebrew qadosh. The word chasid corresponds more with ὅσιος, translated “holy” (1 Tim. 2:8; Titus 1:8; Heb. 7:26; Rev. 15:4); and “Holy One” (Acts 2:27; Acts 13:35).
As there were many saints on the earth in Old Testament times, so we read in the Revelation that there will be saints on the earth after the church has been taken to heaven. Ignorance of this has often led to a mistaken application of the prophecies to the church (Rev. 13:10; Rev. 14:12; Rev. 18:24; Rev. 20:9).

Strong’s Dictionary of Greek Words:

Greek:
ἅγιος
Transliteration:
hagios
Phonic:
hag’-ee-os
Meaning:
from ἅγος (an awful thing) (compare 53, 2282); sacred (physically, pure, morally blameless or religious, ceremonially, consecrated)
KJV Usage:
(most) holy (one, thing), saint