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Genesis 22

Gen. 22:10 KJV (With Strong’s)

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10
And Abraham
'Abraham (Hebrew #85)
father of a multitude; Abraham, the later name of Abram
KJV usage: Abraham.
Pronounce: ab-raw-hawm'
Origin: contracted from 1 and an unused root (probably meaning to be populous)
stretched forth
shalach (Hebrew #7971)
to send away, for, or out (in a great variety of applications)
KJV usage: X any wise, appoint, bring (on the way), cast (away, out), conduct, X earnestly, forsake, give (up), grow long, lay, leave, let depart (down, go, loose), push away, put (away, forth, in, out), reach forth, send (away, forth, out), set, shoot (forth, out), sow, spread, stretch forth (out).
Pronounce: shaw-lakh'
Origin: a primitive root
his hand
yad (Hebrew #3027)
a hand (the open one (indicating power, means, direction, etc.), in distinction from 3709, the closed one); used (as noun, adverb, etc.) in a great variety of applications, both literally and figuratively, both proximate and remote (as follows)
KJV usage: (+ be) able, X about, + armholes, at, axletree, because of, beside, border, X bounty, + broad, (broken-)handed, X by, charge, coast, + consecrate, + creditor, custody, debt, dominion, X enough, + fellowship, force, X from, hand(-staves, -y work), X he, himself, X in, labour, + large, ledge, (left-)handed, means, X mine, ministry, near, X of, X order, ordinance, X our, parts, pain, power, X presumptuously, service, side, sore, state, stay, draw with strength, stroke, + swear, terror, X thee, X by them, X themselves, X thine own, X thou, through, X throwing, + thumb, times, X to, X under, X us, X wait on, (way-)side, where, + wide, X with (him, me, you), work, + yield, X yourselves.
Pronounce: yawd
Origin: a primitive word
, and took
laqach (Hebrew #3947)
to take (in the widest variety of applications)
KJV usage: accept, bring, buy, carry away, drawn, fetch, get, infold, X many, mingle, place, receive(-ing), reserve, seize, send for, take (away, -ing, up), use, win.
Pronounce: law-kakh'
Origin: a primitive root
the knife
ma'akeleth (Hebrew #3979)
something to eat with,- i.e. a knife
KJV usage: knife.
Pronounce: mah-ak-eh'-leth
Origin: from 398
to slay
shachat (Hebrew #7819)
to slaughter (in sacrifice or massacre)
KJV usage: kill, offer, shoot out, slay, slaughter.
Pronounce: shaw-khat'
Origin: a primitive root
his son
ben (Hebrew #1121)
a son (as a builder of the family name), in the widest sense (of literal and figurative relationship, including grandson, subject, nation, quality or condition, etc., (like 1, 251, etc.))
KJV usage: + afflicted, age, (Ahoh-) (Ammon-) (Hachmon-) (Lev-)ite, (anoint-)ed one, appointed to, (+) arrow, (Assyr-) (Babylon-) (Egypt-) (Grec-)ian, one born, bough, branch, breed, + (young) bullock, + (young) calf, X came up in, child, colt, X common, X corn, daughter, X of first, + firstborn, foal, + very fruitful, + postage, X in, + kid, + lamb, (+) man, meet, + mighty, + nephew, old, (+) people, + rebel, + robber, X servant born, X soldier, son, + spark, + steward, + stranger, X surely, them of, + tumultuous one, + valiant(-est), whelp, worthy, young (one), youth.
Pronounce: bane
Origin: from {SI 11129}1129{/SI}
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More on:

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Abraham,
Knife,
Son

Cross References

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Isa. 53:6‑12• 6All we like sheep have gone astray; we have turned every one to his own way; and Jehovah hath laid on him the iniquity of us all.
 7He was oppressed, and he was afflicted, yet he opened not his mouth; he was brought as a lamb to the slaughter, and was as a sheep dumb before her shearers, and he opened not his mouth.
 8He was taken from detention and from judgment: and who shall declare his generation for he was cut off out of the land of the living; for the transgression of my people was he stricken.
 9And they made his grave with the wicked, but [he was] with the rich in his death, because he had done no violence, neither [was there] guile in his mouth.
 10Yet it pleased Jehovah to bruise him; he hath put [him] to grief: when thou shalt make his soul an offering for sin, he shall see a seed, he shall prolong [his] days, and the pleasure of Jehovah shall prosper in his hand.
 11From the travail of his soul shall he see, he shall be satisfied; by his knowledge shall my righteous servant instruct the many in righteousness; and he shall bear their iniquities.
 12Therefore will I assign him [a portion] with the great, and he shall divide the spoil with the strong; because he poured out his soul unto death, and was numbered with the transgressors; and he bore the sin of many, and made intercession for the transgressors. (Isa. 53:6‑12)
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Heb. 11:17‑19• 17By faith Abraham when tried offered up Isaac, and he that received to himself the promises was offering his only-begotten
 18as to whom it was spoken, In Isaac shall thy seed be called;
 19accounting that God [is] able to raise even from out of dead [men], whence also he received him back in parable. (Heb. 11:17‑19)
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James 2:21‑23• 21Was not Abraham our father justified by works, when he offered Isaac his son upon the altar?
 22Thou seest that faith wrought with his works, and by works faith was perfected.
 23And the scripture was fulfilled which saith, Abraham believed God, and it was reckoned to him for righteousness, and he was called Friend of God. (James 2:21‑23)

J. N. Darby Translation

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And Abraham stretched out his hand, and took the knife to slaughter his son.

W. Kelly Translation

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10
And Abraham stretched forth his hand, and took the knife to slay his son.