(be) ignorant(-ly), not know, not understand, unknown

Concise Bible Dictionary:

Both ἀγπὐμματς. And ἰδιώτς are translated ‘unlearned,' but there is a difference between them. Both words occur in Acts 4:13: the rulers of Israel perceived Peter and John to be "unlearned (ἀγ.) and ignorant ἰδ.) men." ἀγράμμος (from a neg. and γράμμαa letter ') occurs nowhere else in the N. T., but γράμμα occurs in John 7:15: "how knoweth this man ‘letters’?" and in Acts 26:24: "much ‘learning ' doth make thee mad." These instances show that a7p,i,a,tucrog signifies ‘unlettered.'
ἰδιώτης (from ἰδιος, ‘one's own') has a different signification: it is applied to private persons in distinction from those who are officials or professionals, and so to simple or uninstructed persons. The apostle asks how such a one could say Amen to the giving of thanks by one speaking in a tongue, not understanding what was said, 1 Cor. 14:16; and in verses 23, 24 he is classed with unbelievers. The word occurs also in 2 Cor. 11:6, where Paul maintains that though he may be simple, or untrained, in speech, he is not so in regard to knowledge.

Strong’s Dictionary of Greek Words:

Greek:
ἀγνοέω
Transliteration:
agnoeo
Phonic:
ag-no-eh’-o
Meaning:
from 1 (as a negative particle) and 3539; not to know (through lack of information or intelligence); by implication, to ignore (through disinclination)
KJV Usage:
(be) ignorant(-ly), not know, not understand, unknown